| Name | Meaning | Gender | Origin |
|---|
| Piper | A pipe player | Female | English |
| Pluto | Wealth, riches | Unisex | Greek |
| Poison | A destructive or fatal substance. | Unisex | English |
| Pokey | | Unisex | Hebrew |
| Pongo | One who smells. | Unisex | English |
| Pookie | | Unisex | Hebrew |
| Popeye | | Unisex | Hebrew |
| Porkchop | | Unisex | Hebrew |
| Porter | One who carries goods | Male | Latin |
| Precious | Loved | Female | English |
| Princess | Royal son | Female | English |
| Psycho | | Unisex | Hebrew |
| Puddin | | Unisex | Hebrew |
| Puddles | | Unisex | Hebrew |
| Pumba | | Unisex | Hebrew |
| Pummy | | Unisex | Hebrew |
| Pumpkin | Large round fruit with orange skin | Unisex | English |
| Quick | Speedy and fast. | Unisex | English |
| Rage | | Unisex | Hebrew |
| Rex | King | Male | Latin |
| Rin | Cold | Unisex | Japanese |
| Roach | | Unisex | Hebrew |
| Rogue | | Unisex | Hebrew |
| Rowdy | Boisterous. Western Nickname. | Unisex | English |
| Rufus | Red | Male | Latin |
| Rusty | Rusty, full of rust | Unisex | American English |
| Sable | Sable (black) | Unisex | English |
| Sandler | After the actor Adam Sandler | Male | English |
| Sarge | Noncommissioned Army or Air Force rank | Unisex | English |
| Sasquatch | Has extra toes and hence is a bigfoot | Unisex | English |