| Name | Meaning | Gender | Origin |
|---|
| Shorty | Of less than average size | Unisex | English |
| Silly | | Unisex | Hebrew |
| Slim | Slender in proportion to height. | Unisex | English |
| Socks | Short stockings finishing above the ankle | Unisex | English |
| Soda | A carbonated water. | Unisex | English |
| Sparky | Animated, lively. | Unisex | English |
| Spot | After Data's cat on Star Trek: The Next Generation | Unisex | English |
| Sprite | Lemonade flavored soft drink. | Unisex | English |
| Squirt | Slang for a small person | Unisex | English |
| Stumpy | A short, thickset person | Unisex | English |
| Sweetie | Sweetheart. | Unisex | English |
| Tango | | Unisex | Hebrew |
| Tinkerbell | | Unisex | Hebrew |
| Tobey | God is good | Unisex | Hebrew |
| Toby | God is good | Unisex | Hebrew |
| Tootsie | A girl or young woman. | Unisex | English |
| Trooper | A state or mounted police officer. Also a member of a cavalry unit. | Unisex | English |
| Twiggy | | Unisex | Hebrew |
| Whiskey | An alcoholic liquor distilled from grain | Unisex | English |
| Wiley | Trapper or hunter | Unisex | English |
| Winnie | Blessed peace | Unisex | Welsh |
| Yoda | | Unisex | Hebrew |