| Name | Meaning | Gender | Origin |
|---|
| Rajah | Anticipation | Unisex | Arabic |
| Rascal | One that is playfully mischievous | Unisex | English |
| Reagan | Descendent of Riagán | Unisex | Gaelic |
| Reggie | Ruler with counsel | Unisex | Germanic |
| Rey | Red | Unisex | Gaelic |
| Rizzo | | Unisex | Hebrew |
| Robbin | Famed: Bright: Shining Form Of Robert Popular Since The Medieval Days Of Robin Hood. Robinson: (English) Son Of Robert Famed: Bright: Shining. Surname. | Unisex | English |
| Romy | Sea dew | Unisex | Latin |
| Ronnie | Ruler with counsel | Unisex | Norse |
| Rowdy | Boisterous. Western Nickname. | Unisex | English |
| Rusty | Rusty, full of rust | Unisex | American English |
| Salem | Secure, peace | Unisex | Arabic |
| Sammy | His name is God | Unisex | Hebrew |
| Sasha | Defending men | Unisex | Greek |
| Sassy | Lively and spirited | Unisex | English |
| Scooby | | Unisex | Hebrew |
| Scooter | One who goes suddenly and speedily. | Unisex | English |
| Scout | Observer | Unisex | American English |
| Seiko | Sincere child | Unisex | Japanese |
| Semolina | | Unisex | Hebrew |
| Shadow | Shadow | Unisex | English |
| Shakespeare | Brandish spear | Unisex | English |
| Shilo | Gift for him | Unisex | Hebrew |
| Shiloh | Gift for him | Unisex | Hebrew |
| Shorty | Of less than average size | Unisex | English |
| Silk | | Unisex | Hebrew |
| Skyler | Guarded | Unisex | Dutch |
| Slim | Slender in proportion to height. | Unisex | English |
| Smoky | | Unisex | Hebrew |
| Snowflake | Single flake or crystal of snow. | Unisex | English |