| Name | Meaning | Gender | Origin |
|---|
| Sloan | Fighter | Male | American English |
| Smokey | A grayish blue colour. Slang for highway patrol officer | Unisex | English |
| Smoky | | Unisex | Hebrew |
| Snappy | cleverly concise; neat | Both | Hebrew |
| Sniper | A skilled shooter who spots targets from a concealed place. | Unisex | English |
| Snow | Snow, fair skinned | Female | English |
| Snowball | | Unisex | Hebrew |
| Snowy | Covered with snow | Female | English |
| Sonia | Wisdom | Female | Greek |
| Sonya | Wisdom | Female | Greek |
| Sophie | Wisdom | Female | Greek |
| Sparky | Animated, lively. | Unisex | English |
| Speedo | A manufacturer and distributor of swimwear and swim-related accessories | Both | English |
| Speedy | Rapid motion, swift. | Unisex | English |
| Spirit | Part of the human being associated with the mind. Vigorous or animated state - spirited. Also distilled alcohol. | Unisex | English |
| Spruce | Evergreen tree | Male | English |
| Star | Star | Female | Latin |
| Stella | Star | Female | Latin |
| Steve | Crown | Male | Greek |
| Storm | Violent weather | Female | English |
| Stormy | Violent weather | Unisex | English |
| Sugar | A sweet powder from sugar cane. Slang for sweetheart. | Female | English |
| Suki | To like | Female | Japanese |
| Supersonic | Exceeds the speed of sound | Both | English |
| Swan | birds of the family Anatidae within the genus Cygnus | Both | English |
| Tahoe | Edge of the lake | Unisex | Native American |
| Taiga | Boreal forest or snow forest | Both | English |
| Talon | A claw | Male | English |
| Tank | A large metal container. A heavily armed combat vehicle | Unisex | English |
| Tara | Crag | Female | Gaelic |