| Name | Meaning | Gender | Origin |
|---|
| Scott | Painted warrior | Male | English |
| Scout | Observer | Unisex | American English |
| Seal | Sea creature | Male | English |
| Serge | Servant | Male | Latin |
| Seth | Appointed | Male | Hebrew |
| Shade | Sweetly singing | Unisex | African |
| Shae | Supplanter | Unisex | Hebrew |
| Shaq | Handsome | Unisex | Arabic |
| Shark | | Unisex | Hebrew |
| Shaw | Grove | Male | English |
| Shay | Supplanter | Male | Hebrew |
| Shea | Hawklike - graceful, free, courageous | Male | Gaelic |
| Sid | Wide meadow | Male | English |
| Sioux | | Unisex | Hebrew |
| Sir | | Unisex | Hebrew |
| Skeet | Swift | Male | English |
| Skip | Master of a Ship | Male | American English |
| Sky | Sky | Unisex | Norse |
| Skye | Cloud | Male | Norse |
| Slade | Valley | Male | English |
| Slash | | Unisex | Hebrew |
| Slate | | Unisex | Hebrew |
| Slim | Slender in proportion to height. | Unisex | English |
| Sloane | Fighter | Unisex | American English |
| Sly | A forest | Unisex | Latin |
| Smith | A smith | Male | English |
| Smudge | A blotch or smear | Unisex | English |
| Sniff | A short inhale through the nose. To savour or investigate a smell. | Unisex | English |
| Snoop | To pry into the private affairs of others | Unisex | English |
| Snow | Snow, fair skinned | Female | English |