| Name | Meaning | Gender | Origin |
|---|
| Shorty | Of less than average size | Unisex | English |
| Silas | Of the forest | Male | Latin |
| Skittles | | Unisex | Hebrew |
| Slim | Slender in proportion to height. | Unisex | English |
| Sloan | Fighter | Male | American English |
| Snowflake | Single flake or crystal of snow. | Unisex | English |
| Sophie | Wisdom | Female | Greek |
| Spencer | Someone who gives out goods | Male | French |
| Speranza | Hope | Female | Italian |
| Sprite | Lemonade flavored soft drink. | Unisex | English |
| Squirt | Slang for a small person | Unisex | English |
| Stumpy | A short, thickset person | Unisex | English |
| Sugar | A sweet powder from sugar cane. Slang for sweetheart. | Female | English |
| Sweetie | Sweetheart. | Unisex | English |
| Taboo | | Unisex | Hebrew |
| Tad | Poet | Male | Gaelic |
| Tama | Jewel | Female | Japanese |
| Tao | Apple | Male | Vietnamese |
| Tavis | Twin | Male | Aramaic |
| Taz | Wild Animal, Thrid Born | Unisex | American |
| Teddy | Gift of God | Male | Greek |
| Teeny | | Unisex | Hebrew |
| Telly | Wise, Best | Unisex | Greek |
| Tess | Harvester | Female | Greek |
| Tilly | Powerful battler | Unisex | Germanic |
| Tink | | Unisex | Hebrew |
| Tinkerbell | | Unisex | Hebrew |
| Tiny | Extremely small | Unisex | English |
| Toby | God is good | Unisex | Hebrew |
| Tootsie | A girl or young woman. | Unisex | English |