| Name | Meaning | Gender | Origin |
|---|
| Quark | Subatomic particle | Unisex | English |
| Queenie | Female ruler | Female | English |
| Rags | | Unisex | Hebrew |
| Ranger | Gamekeeper | Male | English |
| Reno | Ruler with counsel | Unisex | Germanic |
| Rex | King | Male | Latin |
| Rhett | Advice, counsel | Male | English |
| Rocky | Battle cry | Male | Germanic |
| Roscoe | Roe deer wood | Male | Norse |
| Rusty | Rusty, full of rust | Unisex | American English |
| Sam | He is called god | Male | Hebrew |
| Sampson | Sun | Unisex | Hebrew |
| Sasha | Defending men | Unisex | Greek |
| Scooby | | Unisex | Hebrew |
| Shadow | Shadow | Unisex | English |
| Shaggy | Bushy and matted (hair), unkempt. | Unisex | English |
| Sherlock | With cropped hair | Male | English |
| Shorty | Of less than average size | Unisex | English |
| Skip | Master of a Ship | Male | American English |
| Smokey | A grayish blue colour. Slang for highway patrol officer | Unisex | English |
| Sniff | A short inhale through the nose. To savour or investigate a smell. | Unisex | English |
| Snoopy | | Unisex | Hebrew |
| Sparky | Animated, lively. | Unisex | English |
| Spike | A long, thick sharp-pointed piece of wood or metal | Male | English |
| Spot | After Data's cat on Star Trek: The Next Generation | Unisex | English |
| Tarzan | White skin | Unisex | Literary |
| Thor | Thunder | Male | Norse |
| Thunder | Stormy Tempered | Unisex | English |
| Toby | God is good | Unisex | Hebrew |
| Tripod | | Unisex | Hebrew |