| Name | Meaning | Gender | Origin |
|---|
| Simba | Lion | Female | Swahili |
| Slim | Slender in proportion to height. | Unisex | English |
| Sonic | Approaching the speed of sound, fast-paced | Unisex | English |
| Sophia | Wisdom | Female | Greek |
| Sophie | Wisdom | Female | Greek |
| Sparky | Animated, lively. | Unisex | English |
| Squirt | Slang for a small person | Unisex | English |
| Star | Star | Female | Latin |
| Stumpy | A short, thickset person | Unisex | English |
| Sugar | A sweet powder from sugar cane. Slang for sweetheart. | Female | English |
| Suzanne | Lily | Female | Hebrew |
| Sweetie | Sweetheart. | Unisex | English |
| Switch | | Unisex | Hebrew |
| Tank | A large metal container. A heavily armed combat vehicle | Unisex | English |
| Taz | Wild Animal, Thrid Born | Unisex | American |
| Thunder | Stormy Tempered | Unisex | English |
| Tiger | Tiger | Unisex | English |
| Tigga | | Unisex | Hebrew |
| Tina | Follower of Christ | Female | Latin |
| Tiny | Extremely small | Unisex | English |
| Toby | God is good | Unisex | Hebrew |
| Tootsie | A girl or young woman. | Unisex | English |
| Trinity | Threefold | Female | Latin |
| Trixie | Voyager through life | Female | Latin |
| Trouble | A cause of disturbance or difficulty. | Unisex | English |
| Tuppence | British for two pence (coins) | Unisex | English |
| Turbo | Driven by a turbine - turbocharged | Unisex | English |
| Twiggy | | Unisex | Hebrew |
| Velvet | Soft | Female | English |
| Vicki | Conqueror | Female | Latin |