| Name | Meaning | Gender | Origin |
|---|
| Rusty | Rusty, full of rust | Unisex | American English |
| Sabre | | Unisex | Hebrew |
| Sadie | Princess | Female | Hebrew |
| Sailor | Sailor | Unisex | English |
| Sammy | His name is God | Unisex | Hebrew |
| Sasha | Defending men | Unisex | Greek |
| Sassy | Lively and spirited | Unisex | English |
| Savannah | Plateau | Female | Spanish |
| Scarlet | Scarlet | Female | English |
| Scout | Observer | Unisex | American English |
| Shadow | Shadow | Unisex | English |
| Shasta | Name of a Native American tribe | Female | Native American |
| Sheba | Daughter of an oath | Female | Hebrew |
| Sierra | Mountain range | Female | Spanish |
| Smoky | | Unisex | Hebrew |
| Sophie | Wisdom | Female | Greek |
| Sparky | Animated, lively. | Unisex | English |
| Splash | To cause fluid to scatter in flying masses. To display very noticeably. | Unisex | English |
| Stormy | Violent weather | Unisex | English |
| Sugar | A sweet powder from sugar cane. Slang for sweetheart. | Female | English |
| Taco | A folded fried tortilla filled with meat, cheese and spices. | Unisex | English |
| Tamale | | Unisex | Hebrew |
| Tasha | (Christ's) birthday | Female | Latin |
| Tasia | Resurrection | Female | Greek |
| Tequila | An alcoholic liquor distilled from mescal. | Unisex | English |
| Tia | Princess Or Crowned One | Female | English |
| Tiago | Saint James | Unisex | Spanish |
| Tierra | Earth | Female | Spanish |
| Tina | Follower of Christ | Female | Latin |
| Tito | Giant | Unisex | Latin |