| Name | Meaning | Gender | Origin |
| Puddles | | Unisex | Hebrew |
| Pumpkin | Large round fruit with orange skin | Unisex | English |
| Quincy | Fifth | Male | Latin |
| Ralph | Wolf council | Male | Germanic |
| Rascal | One that is playfully mischievous | Unisex | English |
| Raymond | Advice | Male | Germanic |
| Reuben | Behold, a son | Male | Hebrew |
| Rico | Strong power | Male | French |
| Riley | Rye clearing | Male | English |
| Ringo | Apple, peace be with you | Male | English |
| Ripley | Separate | Male | English |
| Rocky | Battle cry | Male | Germanic |
| Sam | He is called god | Male | Hebrew |
| Sammy | His name is God | Unisex | Hebrew |
| Samson | Sun | Male | Hebrew |
| Sandy | Defending men | Male | Greek |
| Sasha | Defending men | Unisex | Greek |
| Sassy | Lively and spirited | Unisex | English |
| Scooby | | Unisex | Hebrew |
| Shadow | Shadow | Unisex | English |
| Shorty | Of less than average size | Unisex | English |
| Sid | Wide meadow | Male | English |
| Skipper | Master of a Ship | Male | American English |
| Slim | Slender in proportion to height. | Unisex | English |
| Sniff | A short inhale through the nose. To savour or investigate a smell. | Unisex | English |
| Sparky | Animated, lively. | Unisex | English |
| Spice | Plant used to flavour food or beverages. | Unisex | English |
| Spike | A long, thick sharp-pointed piece of wood or metal | Male | English |
| Squirt | Slang for a small person | Unisex | English |
| Stumpy | A short, thickset person | Unisex | English |