| Name | Meaning | Gender | Origin |
|---|
| Comet | A celestial body | Unisex | English |
| Conan | Little wolf hound | Male | Gaelic |
| Conner | Lover of hounds | Male | Gaelic |
| Cookie | A small flat, crisp cake | Unisex | English |
| Cooper | Barrel maker | Male | English |
| Copper | A reddish brown metal - as in copper penny coins. Also slang for a police officer. | Unisex | English |
| Corky | Variant Of Corey Hill Hollow. | Unisex | English |
| Cosmo | Order | Male | Greek |
| Cowboy | | Unisex | Hebrew |
| Critter | | Unisex | Hebrew |
| Cuddles | To nestle or snuggle. | Unisex | English |
| Cujo | | Unisex | Hebrew |
| Curly | Having curls or wavy hair. | Unisex | English |
| Cyrano | Shy heart | Male | Greek |
| Dakota | The allies | Female | Native American |
| Dallas | Meadow stance | Male | Gaelic |
| Damen | Calm, Tame | Male | English |
| Dante | Enduring, obstinate | Male | Latin |
| Darth | | Unisex | Hebrew |
| Dash | From Chiel | Male | French |
| Dasher | | Unisex | Hebrew |
| Delta | Fourth letter of the alphabet | Female | Greek |
| Deuce | | Unisex | Hebrew |
| Dexter | Dyer of cloth | Male | English |
| Diablo | The Devil | Unisex | English |
| Diesel | | Unisex | Hebrew |
| Digby | Dyke farm, dyke settlement | Male | English |
| Digger | One that digs. | Unisex | English |
| Dinky | Dog on National Lampoon's Vacation | Unisex | English |
| Dino | From The Dene | Male | Italian |