| Name | Meaning | Gender | Origin |
| Paws | | Unisex | Hebrew |
| Petal | A section of a flower | Unisex | English |
| Pierce | Stone | Male | Greek |
| Quinn | Descendent of Cuinn | Male | Gaelic |
| Rambo | | Unisex | Hebrew |
| Randal | Shield rim | Male | Germanic |
| Rogue | | Unisex | Hebrew |
| Roman | Roman | Unisex | Latin |
| Ronnie | Ruler with counsel | Unisex | Norse |
| Rupert | Bright fame | Male | English |
| Ryan | Little King | Male | Gaelic |
| Rylan | Country of cereal grass | Male | English |
| Sable | Sable (black) | Unisex | English |
| Sabre | | Unisex | Hebrew |
| Sammy | His name is God | Unisex | Hebrew |
| Samson | Sun | Male | Hebrew |
| Sandy | Defending men | Male | Greek |
| Sasha | Defending men | Unisex | Greek |
| Sasquatch | Has extra toes and hence is a bigfoot | Unisex | English |
| Sassy | Lively and spirited | Unisex | English |
| Satan | The Devil and adversary of God | Unisex | English |
| Saturn | Sixth and second largest planet away from the Sun. | Unisex | English |
| Seamus | Form Of James Supplanter. | Male | English |
| Shaggy | Bushy and matted (hair), unkempt. | Unisex | English |
| Shamrock | | Unisex | Hebrew |
| Shark | | Unisex | Hebrew |
| Soda | A carbonated water. | Unisex | English |
| Spike | A long, thick sharp-pointed piece of wood or metal | Male | English |
| Talon | A claw | Male | English |
| Tank | A large metal container. A heavily armed combat vehicle | Unisex | English |