| Name | Meaning | Gender | Origin |
|---|
| Rebecca | To tie | Female | Hebrew |
| Rogue | | Unisex | Hebrew |
| Roman | Roman | Unisex | Latin |
| Rona | Ruler with counsel | Female | Norse |
| Ronnie | Ruler with counsel | Unisex | Norse |
| Rosa | Rose | Female | Latin |
| Rosie | Rose | Female | Latin |
| Roxanne | Star | Female | Persian |
| Roxy | Star | Female | Persian |
| Ruby | Red | Female | Latin |
| Rupert | Bright fame | Male | English |
| Ryan | Little King | Male | Gaelic |
| Rylan | Country of cereal grass | Male | English |
| Sable | Sable (black) | Unisex | English |
| Sabre | | Unisex | Hebrew |
| Sadie | Princess | Female | Hebrew |
| Samantha | Listener | Female | Aramaic |
| Sammy | His name is God | Unisex | Hebrew |
| Samson | Sun | Male | Hebrew |
| Sandy | Defending men | Male | Greek |
| Sasha | Defending men | Unisex | Greek |
| Sasquatch | Has extra toes and hence is a bigfoot | Unisex | English |
| Sassy | Lively and spirited | Unisex | English |
| Satan | The Devil and adversary of God | Unisex | English |
| Satin | Amber | Female | Armenian |
| Saturn | Sixth and second largest planet away from the Sun. | Unisex | English |
| Scarlet | Scarlet | Female | English |
| Seamus | Form Of James Supplanter. | Male | English |
| Shaggy | Bushy and matted (hair), unkempt. | Unisex | English |
| Shamrock | | Unisex | Hebrew |