| Name | Meaning | Gender | Origin |
|---|
| Digby | Dyke farm, dyke settlement | Male | English |
| Digger | One that digs. | Unisex | English |
| Dinah | Judged | Female | Hebrew |
| Dinky | Dog on National Lampoon's Vacation | Unisex | English |
| Dog | Domesticated carnivorous mammal. Dogs exhibit enormous genetic variety with over 2 different breed types. Man's best friend. | Unisex | English |
| Don | World rule | Male | Gaelic |
| Dougal | Black stranger | Male | Gaelic |
| Duchess | From the AristoCats | Unisex | English |
| Dudley | Wood or clearing of Dudda | Male | English |
| Duke | Duke | Male | English |
| Earl | Nobleman | Male | English |
| Earnest | Earnest, serious | Male | Germanic |
| Eddie | Wealth protector | Male | English |
| Edgar | Protector of the good | Male | English |
| Ein | | Unisex | Hebrew |
| Einstein | | Unisex | Hebrew |
| Electra | Shining | Female | Greek |
| Fang | Fragrant | Unisex | Chinese |
| Farley | Fern wood | Male | English |
| Fergus | Man of strength | Male | Gaelic |
| Fifi | He will enlarge | Female | Hebrew |
| Flash | To move rapidly. | Unisex | English |
| Fluffy | Covered with fluff, Soft, light and airy. | Female | English |
| Frank | Javelin | Male | Germanic |
| Fred | Peaceful ruler | Male | Germanic |
| Freeway | | Unisex | Hebrew |
| Frodo | Wise by experience | Unisex | Literary |
| Gin | Silvery | Female | English |
| Ginger | Spring-like | Female | Latin |
| Gnasher | | Unisex | Hebrew |