| Name | Meaning | Gender | Origin |
|---|
| Shadow | Shadow | Unisex | English |
| Shakespeare | Brandish spear | Unisex | English |
| Shamrock | | Unisex | Hebrew |
| Shark | | Unisex | Hebrew |
| Shay | Supplanter | Male | Hebrew |
| Sheba | Daughter of an oath | Female | Hebrew |
| Shelby | A place where willows grow | Female | American English |
| Sherlock | With cropped hair | Male | English |
| Shona | God is gracious | Female | Hebrew |
| Shorty | Of less than average size | Unisex | English |
| Sienna | Reddish orange-brown | Female | Italian |
| Sierra | Mountain range | Female | Spanish |
| Sigma | | Unisex | Hebrew |
| Silver | Silver (the metal or colour) | Male | English |
| Silvia | Wooded | Female | Latin |
| Simba | Lion | Female | Swahili |
| Simone | Listening | Female | Hebrew |
| Skittles | | Unisex | Hebrew |
| Sky | Sky | Unisex | Norse |
| Skye | Cloud | Male | Norse |
| Slim | Slender in proportion to height. | Unisex | English |
| Smokie | | Unisex | Hebrew |
| Smoky | | Unisex | Hebrew |
| Snowball | | Unisex | Hebrew |
| Snowflake | Single flake or crystal of snow. | Unisex | English |
| Socks | Short stockings finishing above the ankle | Unisex | English |
| Solomon | Peace | Male | Hebrew |
| Sonic | Approaching the speed of sound, fast-paced | Unisex | English |
| Sophia | Wisdom | Female | Greek |
| Sophie | Wisdom | Female | Greek |