| Name | Meaning | Gender | Origin |
|---|
| Samson | Sun | Male | Hebrew |
| Sandy | Defending men | Male | Greek |
| Sara | Princess | Female | Hebrew |
| Sarah | Princess | Female | Hebrew |
| Sasha | Defending men | Unisex | Greek |
| Sassy | Lively and spirited | Unisex | English |
| Scout | Observer | Unisex | American English |
| Shadow | Shadow | Unisex | English |
| Sheba | Daughter of an oath | Female | Hebrew |
| Simba | Lion | Female | Swahili |
| Simon | Listening | Male | Hebrew |
| Smoky | | Unisex | Hebrew |
| Sniper | A skilled shooter who spots targets from a concealed place. | Unisex | English |
| Socrates | Uncertain meaning | Male | Greek |
| Sofia | Wisdom | Female | Greek |
| Sophie | Wisdom | Female | Greek |
| Sparky | Animated, lively. | Unisex | English |
| Spaz | For a spazy kitty | Unisex | English |
| Speedy | Rapid motion, swift. | Unisex | English |
| Spike | A long, thick sharp-pointed piece of wood or metal | Male | English |
| Stan | Meadow that is stony | Male | English |
| Sugar | A sweet powder from sugar cane. Slang for sweetheart. | Female | English |
| Taco | A folded fried tortilla filled with meat, cheese and spices. | Unisex | English |
| Tasha | (Christ's) birthday | Female | Latin |
| Taz | Wild Animal, Thrid Born | Unisex | American |
| Teddy | Gift of God | Male | Greek |
| Tess | Harvester | Female | Greek |
| Thomas | Twin | Male | Aramaic |
| Thor | Thunder | Male | Norse |
| Toby | God is good | Unisex | Hebrew |