| Name | Meaning | Gender | Origin |
|---|
| Sheba | Daughter of an oath | Female | Hebrew |
| Shiloh | Gift for him | Unisex | Hebrew |
| Sierra | Mountain range | Female | Spanish |
| Silver | Silver (the metal or colour) | Male | English |
| Simba | Lion | Female | Swahili |
| Sky | Sky | Unisex | Norse |
| Smirnoff | | Unisex | Hebrew |
| Smokey | A grayish blue colour. Slang for highway patrol officer | Unisex | English |
| Smoky | | Unisex | Hebrew |
| Snow | Snow, fair skinned | Female | English |
| Snowflake | Single flake or crystal of snow. | Unisex | English |
| Sonya | Wisdom | Female | Greek |
| Sophie | Wisdom | Female | Greek |
| Sparky | Animated, lively. | Unisex | English |
| Spirit | Part of the human being associated with the mind. Vigorous or animated state - spirited. Also distilled alcohol. | Unisex | English |
| Spring | To burst forth | Female | English |
| Star | Star | Female | Latin |
| Storm | Violent weather | Female | English |
| Sugar | A sweet powder from sugar cane. Slang for sweetheart. | Female | English |
| Sunbeam | | Unisex | Hebrew |
| Sunshine | Light from the sun | Unisex | English |
| Tahoe | Edge of the lake | Unisex | Native American |
| Tank | A large metal container. A heavily armed combat vehicle | Unisex | English |
| Tanker | | Unisex | Hebrew |
| Tasha | (Christ's) birthday | Female | Latin |
| Teddy | Gift of God | Male | Greek |
| Terminator | | Unisex | Hebrew |
| Terra | Earth, soil | Female | Latin |
| Thor | Thunder | Male | Norse |
| Thunder | Stormy Tempered | Unisex | English |