| Name | Meaning | Gender | Origin |
|---|
| Red | Red | Unisex | English |
| Reed | Red | Unisex | English |
| Riley | Rye clearing | Male | English |
| Ring | Ring | Male | English |
| River | River | Unisex | English |
| Rocky | Battle cry | Male | Germanic |
| Sable | Sable (black) | Unisex | English |
| Sage | Aromatic herb | Unisex | English |
| Sam | He is called god | Male | Hebrew |
| Sammy | His name is God | Unisex | Hebrew |
| Sandy | Defending men | Male | Greek |
| Sasha | Defending men | Unisex | Greek |
| Sassy | Lively and spirited | Unisex | English |
| Seven | Seven | Unisex | American English |
| Shepherd | One who guards sheeps | Male | English |
| Shorty | Of less than average size | Unisex | English |
| Silk | | Unisex | Hebrew |
| Silver | Silver (the metal or colour) | Male | English |
| Sky | Sky | Unisex | Norse |
| Slim | Slender in proportion to height. | Unisex | English |
| Small | | Unisex | Hebrew |
| Snickers | A brand of candy bar. | Unisex | English |
| Sparky | Animated, lively. | Unisex | English |
| Spencer | Someone who gives out goods | Male | French |
| Spike | A long, thick sharp-pointed piece of wood or metal | Male | English |
| Squirt | Slang for a small person | Unisex | English |
| Stumpy | A short, thickset person | Unisex | English |
| Suger | | Unisex | Hebrew |
| Sunny | Filled with sunlight | Male | English |
| Sweetie | Sweetheart. | Unisex | English |