| Name | Meaning | Gender | Origin |
|---|
| Sadie | Princess | Female | Hebrew |
| Saffron | From the spice or the colour, yellow | Female | English |
| Samantha | Listener | Female | Aramaic |
| Sashi | Moonbeam | Female | Hindu |
| Saskia | Saxon woman | Female | Dutch |
| Satan | The Devil and adversary of God | Unisex | English |
| Satin | Amber | Female | Armenian |
| Scarlet | Scarlet | Female | English |
| Selina | Moon | Female | Greek |
| Shelby | A place where willows grow | Female | American English |
| Sierra | Mountain range | Female | Spanish |
| Silvana | Of the forest | Female | Latin |
| Sooty | Covered with soot | Unisex | English |
| Sophie | Wisdom | Female | Greek |
| Spot | After Data's cat on Star Trek: The Next Generation | Unisex | English |
| Suzy | Lily | Female | Hebrew |
| Tabitha | Gazelle | Female | Aramaic |
| Taboo | | Unisex | Hebrew |
| Tamara | Palm tree | Female | Hebrew |
| Tank | A large metal container. A heavily armed combat vehicle | Unisex | English |
| Tara | Crag | Female | Gaelic |
| Taylor | A tailor | Female | English |
| Tempest | Storm | Female | English |
| Tessa | Harvester | Female | Greek |
| Tiny | Extremely small | Unisex | English |
| Titan | Powerful big man | Unisex | Greek |
| Toby | God is good | Unisex | Hebrew |
| Tori | Conqueror | Female | Latin |
| Trojan | | Unisex | Hebrew |
| Truffles | Ball shaped chocolate | Unisex | English |