| Name | Meaning | Gender | Origin |
|---|
| Sanders | Defending men | Male | Greek |
| Sanford | Sand ford | Male | English |
| Satchel | Sack | Male | English |
| Sebastian | Man from Sebaste | Male | Latin |
| Serena | Composed | Female | Latin |
| Shani | Crimson | Female | Hebrew |
| Shaq | Handsome | Unisex | Arabic |
| Shaquille | Handsome | Male | Arabic |
| Sheila | Blind | Female | Latin |
| Sheryl | Dear one | Female | French |
| Skeet | Swift | Male | English |
| Slate | | Unisex | Hebrew |
| Sonja | Wisdom | Female | Greek |
| Sonny | Son | Male | English |
| Sonya | Wisdom | Female | Greek |
| Spalding | A field divided | Male | English |
| Speed | Success | Unisex | English |
| Spencer | Someone who gives out goods | Male | French |
| Spike | A long, thick sharp-pointed piece of wood or metal | Male | English |
| Starr | Star | Female | Latin |
| Stephan | Crown | Male | Greek |
| Sterling | Little star - stellar | Male | English |
| Stewart | Guardian of the house | Male | English |
| Stitch | After the character in the Lilo And Stitch cartoon | Unisex | English |
| Susanna | Lily | Female | Hebrew |
| Svetlana | Light | Female | Russian |
| Tate | "Pleasant And Bright."Some Variants Are Tait, Taite, And Tayte. | Female | English |
| Tatiana | Variant Of An Ancient Italian Name; Myth Name | Female | Latin |
| Teddy | Gift of God | Male | Greek |
| Terry | Ruler of the people | Unisex | Germanic |