| Name | Meaning | Gender | Origin |
|---|
| Rufus | Red | Male | Latin |
| Sable | Sable (black) | Unisex | English |
| Sabre | | Unisex | Hebrew |
| Samson | Sun | Male | Hebrew |
| Sandy | Defending men | Male | Greek |
| Sara | Princess | Female | Hebrew |
| Sasha | Defending men | Unisex | Greek |
| Sasquatch | Has extra toes and hence is a bigfoot | Unisex | English |
| Satan | The Devil and adversary of God | Unisex | English |
| Satin | Amber | Female | Armenian |
| Saturn | Sixth and second largest planet away from the Sun. | Unisex | English |
| Scarlet | Scarlet | Female | English |
| Shadow | Shadow | Unisex | English |
| Shark | | Unisex | Hebrew |
| Sheba | Daughter of an oath | Female | Hebrew |
| Shelby | A place where willows grow | Female | American English |
| Sierra | Mountain range | Female | Spanish |
| Sky | Sky | Unisex | Norse |
| Sophie | Wisdom | Female | Greek |
| Star | Star | Female | Latin |
| Stella | Star | Female | Latin |
| Stormy | Violent weather | Unisex | English |
| Sugar | A sweet powder from sugar cane. Slang for sweetheart. | Female | English |
| Sun | Goodness | Female | Korean |
| Tank | A large metal container. A heavily armed combat vehicle | Unisex | English |
| Tara | Crag | Female | Gaelic |
| Taryn | King Of Rocky Hill. Variant Of Tarynn. | Female | American English |
| Tex | Of Texas | Unisex | English |
| Theobold | Boldest | Male | German |
| Thor | Thunder | Male | Norse |