| Name | Meaning | Gender | Origin |
|---|
| Rosie | Rose | Female | Latin |
| Roxy | Star | Female | Persian |
| Rusty | Rusty, full of rust | Unisex | American English |
| Sable | Sable (black) | Unisex | English |
| Sabre | | Unisex | Hebrew |
| Sadie | Princess | Female | Hebrew |
| Saige | Aromatic herb | Female | English |
| Samantha | Listener | Female | Aramaic |
| Sammy | His name is God | Unisex | Hebrew |
| Sasha | Defending men | Unisex | Greek |
| Sasquatch | Has extra toes and hence is a bigfoot | Unisex | English |
| Satan | The Devil and adversary of God | Unisex | English |
| Saturn | Sixth and second largest planet away from the Sun. | Unisex | English |
| Scarlet | Scarlet | Female | English |
| Scooby | | Unisex | Hebrew |
| Shark | | Unisex | Hebrew |
| Sheba | Daughter of an oath | Female | Hebrew |
| Shelby | A place where willows grow | Female | American English |
| Smokey | A grayish blue colour. Slang for highway patrol officer | Unisex | English |
| Smoky | | Unisex | Hebrew |
| Sophie | Wisdom | Female | Greek |
| Sun | Goodness | Female | Korean |
| Tango | | Unisex | Hebrew |
| Tank | A large metal container. A heavily armed combat vehicle | Unisex | English |
| Taryn | King Of Rocky Hill. Variant Of Tarynn. | Female | American English |
| Tex | Of Texas | Unisex | English |
| Themis | Order | Unisex | Greek |
| Thunder | Stormy Tempered | Unisex | English |
| Titan | Powerful big man | Unisex | Greek |
| Trinity | Threefold | Female | Latin |