| Name | Meaning | Gender | Origin |
|---|
| Smokey | A grayish blue colour. Slang for highway patrol officer | Unisex | English |
| Snickers | A brand of candy bar. | Unisex | English |
| Snoopy | | Unisex | Hebrew |
| Socks | Short stockings finishing above the ankle | Unisex | English |
| Spanky | | Unisex | Hebrew |
| Sparky | Animated, lively. | Unisex | English |
| Speedy | Rapid motion, swift. | Unisex | English |
| Spike | A long, thick sharp-pointed piece of wood or metal | Male | English |
| Spot | After Data's cat on Star Trek: The Next Generation | Unisex | English |
| Sprite | Lemonade flavored soft drink. | Unisex | English |
| Spud | Slang for potato. | Unisex | English |
| Spunky | Spirited, plucky. | Unisex | English |
| Stephen | Crown | Male | Greek |
| Stormy | Violent weather | Unisex | English |
| Sylvester | A forest | Male | Latin |
| Tango | | Unisex | Hebrew |
| Taran | Heaven | Unisex | Indian |
| Tarzan | White skin | Unisex | Literary |
| Thaddeus | Uncertain, perhaps praised or heart | Male | Aramaic |
| Theo | Gift of God | Male | Greek |
| Thomas | Twin | Male | Aramaic |
| Thumper | To walk with heavy steps | Unisex | English |
| Thunder | Stormy Tempered | Unisex | English |
| Tiger | Tiger | Unisex | English |
| Tigger | From Winnie the Pooh | Unisex | English |
| Timmy | To honor God, to fear God | Male | Greek |
| Toby | God is good | Unisex | Hebrew |
| Toffee | A hard brown, chewy candy | Unisex | English |
| Tom | Twin | Male | Aramaic |
| Tommy | Twin | Male | Aramaic |