| Name | Meaning | Gender | Origin |
|---|
| Paws | | Unisex | Hebrew |
| Petey | Stone | Unisex | Greek |
| Pluto | Wealth, riches | Unisex | Greek |
| Pogo | | Unisex | Hebrew |
| Porkchop | | Unisex | Hebrew |
| Pretzel | Glazed, salted and brittle biscuit in the form of a knot or stick. | Unisex | English |
| Radar | | Unisex | Hebrew |
| Rambo | | Unisex | Hebrew |
| Rascal | One that is playfully mischievous | Unisex | English |
| Reagan | Descendent of Riagán | Unisex | Gaelic |
| Rebel | One that resists of defies authority | Unisex | English |
| Rocket | To move swiftly and powerfully | Unisex | English |
| Rogue | | Unisex | Hebrew |
| Rusty | Rusty, full of rust | Unisex | American English |
| Ryder | One who rides | Unisex | English |
| Sable | Sable (black) | Unisex | English |
| Sage | Aromatic herb | Unisex | English |
| Sailor | Sailor | Unisex | English |
| Sarge | Noncommissioned Army or Air Force rank | Unisex | English |
| Scamper | | Unisex | Hebrew |
| Scooby | | Unisex | Hebrew |
| Scooter | One who goes suddenly and speedily. | Unisex | English |
| Scotch | Scotch whiskey. | Unisex | English |
| Scout | Observer | Unisex | American English |
| Shadow | Shadow | Unisex | English |
| Skippy | Master of a Ship | Unisex | American English |
| Slate | | Unisex | Hebrew |
| Smokey | A grayish blue colour. Slang for highway patrol officer | Unisex | English |
| Snake | | Unisex | Hebrew |
| Snickers | A brand of candy bar. | Unisex | English |