| Name | Meaning | Gender | Origin |
|---|
| Puddles | | Unisex | Hebrew |
| Pumpkin | Large round fruit with orange skin | Unisex | English |
| Puppy | | Unisex | Hebrew |
| Raider | | Unisex | Hebrew |
| Rascal | One that is playfully mischievous | Unisex | English |
| Razzle | | Unisex | Hebrew |
| Red | Red | Unisex | English |
| Ripple | | Unisex | Hebrew |
| River | River | Unisex | English |
| Rocket | To move swiftly and powerfully | Unisex | English |
| Rodeo | | Unisex | Hebrew |
| Ronnie | Ruler with counsel | Unisex | Norse |
| Rusty | Rusty, full of rust | Unisex | American English |
| Ryder | One who rides | Unisex | English |
| Sammy | His name is God | Unisex | Hebrew |
| Sampson | Sun | Unisex | Hebrew |
| Sarge | Noncommissioned Army or Air Force rank | Unisex | English |
| Sasha | Defending men | Unisex | Greek |
| Sassy | Lively and spirited | Unisex | English |
| Scooter | One who goes suddenly and speedily. | Unisex | English |
| Scotch | Scotch whiskey. | Unisex | English |
| Shadow | Shadow | Unisex | English |
| Shelly | Clearing near a ledge | Unisex | English |
| Shiloh | Gift for him | Unisex | Hebrew |
| Shorty | Of less than average size | Unisex | English |
| Slim | Slender in proportion to height. | Unisex | English |
| Snoopy | | Unisex | Hebrew |
| Snowflake | Single flake or crystal of snow. | Unisex | English |
| Sonic | Approaching the speed of sound, fast-paced | Unisex | English |
| Sparkle | To shine with animation | Unisex | English |