| Name | Meaning | Gender | Origin |
|---|
| Saturn | Sixth and second largest planet away from the Sun. | Unisex | English |
| Scooter | One who goes suddenly and speedily. | Unisex | English |
| Scout | Observer | Unisex | American English |
| Shadow | Shadow | Unisex | English |
| Shark | | Unisex | Hebrew |
| Sheridan | Long lived treasure | Unisex | Gaelic |
| Shiloh | Gift for him | Unisex | Hebrew |
| Shorty | Of less than average size | Unisex | English |
| Slim | Slender in proportion to height. | Unisex | English |
| Sly | A forest | Unisex | Latin |
| Snoop | To pry into the private affairs of others | Unisex | English |
| Snoopy | | Unisex | Hebrew |
| Spanky | | Unisex | Hebrew |
| Spice | Plant used to flavour food or beverages. | Unisex | English |
| Spirit | Part of the human being associated with the mind. Vigorous or animated state - spirited. Also distilled alcohol. | Unisex | English |
| Squirt | Slang for a small person | Unisex | English |
| Stumpy | A short, thickset person | Unisex | English |
| Sweetie | Sweetheart. | Unisex | English |
| Tango | | Unisex | Hebrew |
| Tank | A large metal container. A heavily armed combat vehicle | Unisex | English |
| Taz | Wild Animal, Thrid Born | Unisex | American |
| Telly | Wise, Best | Unisex | Greek |
| Tex | Of Texas | Unisex | English |
| Thunder | Stormy Tempered | Unisex | English |
| Tilly | Powerful battler | Unisex | Germanic |
| Tiny | Extremely small | Unisex | English |
| Titan | Powerful big man | Unisex | Greek |
| Toby | God is good | Unisex | Hebrew |
| Tootsie | A girl or young woman. | Unisex | English |
| Tory | Conqueror | Unisex | Latin |