| Name | Meaning | Gender | Origin |
|---|
| Ophelia | Help | Female | Greek |
| Oracle | | Unisex | Hebrew |
| Panther | A black leopard | Unisex | English |
| Pepper | Pepper | Female | English |
| Petey | Stone | Unisex | Greek |
| Phantom | Something elusive. A ghost | Unisex | English |
| Poison | A destructive or fatal substance. | Unisex | English |
| Porkchop | | Unisex | Hebrew |
| Psycho | | Unisex | Hebrew |
| Rage | | Unisex | Hebrew |
| Rambo | | Unisex | Hebrew |
| Ramona | Advice | Female | Germanic |
| Reagan | Descendent of Riagán | Unisex | Gaelic |
| Rebel | One that resists of defies authority | Unisex | English |
| Reno | Ruler with counsel | Unisex | Germanic |
| Rogue | | Unisex | Hebrew |
| Rosemary | Sea dew | Female | Latin |
| Ruby | Red | Female | Latin |
| Rue | Fame | Female | German |
| Ryder | One who rides | Unisex | English |
| Sable | Sable (black) | Unisex | English |
| Sabrina | A Welsh river name | Female | Gaelic |
| Salem | Secure, peace | Unisex | Arabic |
| Sarge | Noncommissioned Army or Air Force rank | Unisex | English |
| Sasquatch | Has extra toes and hence is a bigfoot | Unisex | English |
| Scar | From The Lion King | Unisex | English |
| Scotch | Scotch whiskey. | Unisex | English |
| Shadow | Shadow | Unisex | English |
| Skinner | | Unisex | Hebrew |
| Smokey | A grayish blue colour. Slang for highway patrol officer | Unisex | English |