| Name | Meaning | Gender | Origin |
|---|
| Sarge | Noncommissioned Army or Air Force rank | Unisex | English |
| Sasquatch | Has extra toes and hence is a bigfoot | Unisex | English |
| Scar | From The Lion King | Unisex | English |
| Scotch | Scotch whiskey. | Unisex | English |
| Seraphim | An Angel Like Being Of A Lower Order | Male | English |
| Shadow | Shadow | Unisex | English |
| Shepherd | One who guards sheeps | Male | English |
| Sherman | One who shears cloth | Male | English |
| Skinner | | Unisex | Hebrew |
| Smokey | A grayish blue colour. Slang for highway patrol officer | Unisex | English |
| Snake | | Unisex | Hebrew |
| Sniper | A skilled shooter who spots targets from a concealed place. | Unisex | English |
| Spider | An eight legged insect | Unisex | English |
| Spike | A long, thick sharp-pointed piece of wood or metal | Male | English |
| Spirit | Part of the human being associated with the mind. Vigorous or animated state - spirited. Also distilled alcohol. | Unisex | English |
| Storm | Violent weather | Female | English |
| Sylvester | A forest | Male | Latin |
| Tabitha | Gazelle | Female | Aramaic |
| Tank | A large metal container. A heavily armed combat vehicle | Unisex | English |
| Taz | Wild Animal, Thrid Born | Unisex | American |
| T-bone | A thick steak containing a T shaped bone. | Unisex | English |
| Tempest | Storm | Female | English |
| Tequila | An alcoholic liquor distilled from mescal. | Unisex | English |
| Terminator | | Unisex | Hebrew |
| Thor | Thunder | Male | Norse |
| Tiger | Tiger | Unisex | English |
| Tito | Giant | Unisex | Latin |
| Tomcat | | Unisex | Hebrew |
| Trinity | Threefold | Female | Latin |
| Trip | Traveler | Unisex | English |