| Name | Meaning | Gender | Origin |
|---|
| Sasha | Defending men | Unisex | Greek |
| Sasquatch | Has extra toes and hence is a bigfoot | Unisex | English |
| Sassy | Lively and spirited | Unisex | English |
| Satan | The Devil and adversary of God | Unisex | English |
| Saturn | Sixth and second largest planet away from the Sun. | Unisex | English |
| Senta | Conquering | Female | Latin |
| Serilda | Armored Battle Maiden | Female | English |
| Shark | | Unisex | Hebrew |
| Shasta | Name of a Native American tribe | Female | Native American |
| Sheba | Daughter of an oath | Female | Hebrew |
| Shelby | A place where willows grow | Female | American English |
| Sierra | Mountain range | Female | Spanish |
| Snowflake | Single flake or crystal of snow. | Unisex | English |
| Sophie | Wisdom | Female | Greek |
| Sugar | A sweet powder from sugar cane. Slang for sweetheart. | Female | English |
| Sun | Goodness | Female | Korean |
| Suzanne | Lily | Female | Hebrew |
| Tank | A large metal container. A heavily armed combat vehicle | Unisex | English |
| Taryn | King Of Rocky Hill. Variant Of Tarynn. | Female | American English |
| Tasha | (Christ's) birthday | Female | Latin |
| Tempest | Storm | Female | English |
| Tex | Of Texas | Unisex | English |
| Thunder | Stormy Tempered | Unisex | English |
| Titan | Powerful big man | Unisex | Greek |
| Tresa | Harvester | Female | Greek |
| Trojan | | Unisex | Hebrew |
| Truda | Fighting Woman | Female | English |
| Trude | Strength | Female | Germanic |
| Whisky | | Unisex | Hebrew |
| Whitney | White island | Female | English |