| Name | Meaning | Gender | Origin |
|---|
| Sabre | | Unisex | Hebrew |
| Sam | He is called god | Male | Hebrew |
| Sammy | His name is God | Unisex | Hebrew |
| Samson | Sun | Male | Hebrew |
| Sandy | Defending men | Male | Greek |
| Saphire | Beautiful jewel | Unisex | Greek |
| Sasha | Defending men | Unisex | Greek |
| Sasquatch | Has extra toes and hence is a bigfoot | Unisex | English |
| Satan | The Devil and adversary of God | Unisex | English |
| Saturn | Sixth and second largest planet away from the Sun. | Unisex | English |
| Seth | Appointed | Male | Hebrew |
| Shark | | Unisex | Hebrew |
| Sigmund | Protector | Male | German |
| Simon | Listening | Male | Hebrew |
| Snapper | | Unisex | Hebrew |
| Socks | Short stockings finishing above the ankle | Unisex | English |
| Solomon | Peace | Male | Hebrew |
| Sooty | Covered with soot | Unisex | English |
| Spike | A long, thick sharp-pointed piece of wood or metal | Male | English |
| Talon | A claw | Male | English |
| Tank | A large metal container. A heavily armed combat vehicle | Unisex | English |
| Teddy | Gift of God | Male | Greek |
| Terminator | | Unisex | Hebrew |
| Tex | Of Texas | Unisex | English |
| Thatcher | Roof repairer | Male | English |
| Theo | Gift of God | Male | Greek |
| Thunder | Stormy Tempered | Unisex | English |
| Timmy | To honor God, to fear God | Male | Greek |
| Titan | Powerful big man | Unisex | Greek |
| Toby | God is good | Unisex | Hebrew |