| Name | Meaning | Gender | Origin |
|---|
| Sable | Sable (black) | Unisex | English |
| Sage | Aromatic herb | Unisex | English |
| Salem | Secure, peace | Unisex | Arabic |
| Salvador | Saviour | Male | Latin |
| Sanford | Sand ford | Male | English |
| Seaton | Town by the ocean | Male | English |
| Sebastian | Man from Sebaste | Male | Latin |
| Sedona | | Unisex | Hebrew |
| Seth | Appointed | Male | Hebrew |
| Seward | Victory Guard of the Coast | Male | English |
| Seymour | Moor | Male | Latin |
| Shamrock | | Unisex | Hebrew |
| Shaw | Grove | Male | English |
| Sheldon | Protected hill | Male | English |
| Shelley | Clearing near a ledge | Male | English |
| Shelton | A ledge - literally shelf town | Male | English |
| Sherwood | Bright, wooded glen | Male | English |
| Shiloh | Gift for him | Unisex | Hebrew |
| Sidney | Wide meadow | Male | English |
| Silver | Silver (the metal or colour) | Male | English |
| Sinclair | Saint Clair meaning holy light | Male | English |
| Sky | Sky | Unisex | Norse |
| Skye | Cloud | Male | Norse |
| Slade | Valley | Male | English |
| Snowden | From The Snowy Hill | Male | English |
| Spalding | A field divided | Male | English |
| Spencer | Someone who gives out goods | Male | French |
| Spike | A long, thick sharp-pointed piece of wood or metal | Male | English |
| Stanley | Meadow that is stony | Male | English |
| Stockton | Tree trunk settlement | Male | English |