| Name | Meaning | Gender | Origin |
|---|
| Selby | A place where willows grow | Female | American English |
| Semele | Myth Name (Mother Of Dionysus) | Female | English |
| September | From the month | Female | Latin |
| Sequoia | Large Tree | Female | Native American |
| Serenity | Peacefulness | Female | English |
| Seth | Appointed | Male | Hebrew |
| Seward | Victory Guard of the Coast | Male | English |
| Seymour | Moor | Male | Latin |
| Shamrock | | Unisex | Hebrew |
| Shania | Beautiful | Female | Yiddish |
| Shannon | God is gracious | Female | Hebrew |
| Sharon | The plains | Female | Hebrew |
| Shasta | Name of a Native American tribe | Female | Native American |
| Shaw | Grove | Male | English |
| Shawnee | Tribal name | Female | Native American |
| Shelby | A place where willows grow | Female | American English |
| Sheldon | Protected hill | Male | English |
| Shelley | Clearing near a ledge | Male | English |
| Shelton | A ledge - literally shelf town | Male | English |
| Sherwood | Bright, wooded glen | Male | English |
| Shiloh | Gift for him | Unisex | Hebrew |
| Shirley | Bright grassland | Female | English |
| Sidney | Wide meadow | Male | English |
| Sidonia | Man from Sidon | Female | Latin |
| Sierra | Mountain range | Female | Spanish |
| Silver | Silver (the metal or colour) | Male | English |
| Sinclair | Saint Clair meaning holy light | Male | English |
| Sky | Sky | Unisex | Norse |
| Skye | Cloud | Male | Norse |
| Slade | Valley | Male | English |