| Name | Meaning | Gender | Origin |
|---|
| Runt | | Unisex | Hebrew |
| Sarge | Noncommissioned Army or Air Force rank | Unisex | English |
| Scar | From The Lion King | Unisex | English |
| Scuttle | | Unisex | Hebrew |
| Skinner | | Unisex | Hebrew |
| Skippy | Master of a Ship | Unisex | American English |
| Sleepy | | Unisex | Hebrew |
| Slim | Slender in proportion to height. | Unisex | English |
| Slinky | | Unisex | Hebrew |
| Smee | | Unisex | Hebrew |
| Sneezy | | Unisex | Hebrew |
| Spot | After Data's cat on Star Trek: The Next Generation | Unisex | English |
| Stitch | After the character in the Lilo And Stitch cartoon | Unisex | English |
| Stretch | To extend to full length. | Unisex | English |
| Sulley | Keen eye | Unisex | Gaelic |
| Taran | Heaven | Unisex | Indian |
| Tarzan | White skin | Unisex | Literary |
| Thumper | To walk with heavy steps | Unisex | English |
| Tigger | From Winnie the Pooh | Unisex | English |
| Tinkerbell | | Unisex | Hebrew |
| Tiny | Extremely small | Unisex | English |
| Tito | Giant | Unisex | Latin |
| Toby | God is good | Unisex | Hebrew |
| Trigger | | Unisex | Hebrew |
| Winifred | Blessed peace | Unisex | Welsh |
| Ziggy | Victory protection | Unisex | Germanic |