| Name | Meaning | Gender | Origin |
|---|
| Sam | He is called god | Male | Hebrew |
| Sandra | Defending men | Female | Greek |
| Sandy | Defending men | Male | Greek |
| Sarah | Princess | Female | Hebrew |
| Skipper | Master of a Ship | Male | American English |
| Skittles | | Unisex | Hebrew |
| Smeagol | | Unisex | Hebrew |
| Smidge | | Unisex | Hebrew |
| Smokey | A grayish blue colour. Slang for highway patrol officer | Unisex | English |
| Snowy | Covered with snow | Female | English |
| Sophie | Wisdom | Female | Greek |
| Sprite | Lemonade flavored soft drink. | Unisex | English |
| Sprocket | | Unisex | Hebrew |
| Sprout | | Unisex | Hebrew |
| Squiggy | | Unisex | Hebrew |
| Steffi | Crown | Female | Greek |
| Stephanie | Crowned In Victory | Female | English |
| Sushi | Raw fish. | Unisex | English |
| Tatiana | Variant Of An Ancient Italian Name; Myth Name | Female | Latin |
| Teeny | | Unisex | Hebrew |
| Thumper | To walk with heavy steps | Unisex | English |
| Tiara | A three-tiered crown | Female | English |
| Tiegan | Little Princess In The Big Valley | Female | Native American |
| Tink | | Unisex | Hebrew |
| Tinkerbell | | Unisex | Hebrew |
| Titania | Uncertain, perhaps of the Titans | Female | Latin |
| Tito | Giant | Unisex | Latin |
| Tommy | Twin | Male | Aramaic |
| Tucker | Someone who folds cloth | Male | English |
| Tuppence | British for two pence (coins) | Unisex | English |