| Name | Meaning | Gender | Origin |
| Spalding | A field divided | Male | English |
| Spirit | Part of the human being associated with the mind. Vigorous or animated state - spirited. Also distilled alcohol. | Unisex | English |
| Spooky | | Unisex | Hebrew |
| Spot | After Data's cat on Star Trek: The Next Generation | Unisex | English |
| Sprinkles | | Unisex | Hebrew |
| Starbuck | Star Deer | Unisex | English |
| Sterling | Little star - stellar | Male | English |
| Stone | Stone | Male | English |
| Suede | Swedish | Unisex | English |
| Sullivan | Keen eye | Male | Gaelic |
| Sundance | | Unisex | Hebrew |
| Sunil | Dark blue | Male | Sanskrit |
| Sunny | Filled with sunlight | Male | English |
| Sunshine | Light from the sun | Unisex | English |
| Tan | New, Chastity | Male | English |
| Tanner | Tanner | Male | English |
| Teal | The Bird Teal: Also The Blue-Green Color. | Unisex | English |
| Teddy | Gift of God | Male | Greek |
| Tequila | An alcoholic liquor distilled from mescal. | Unisex | English |
| Thanh | Bright, clear blue | Male | Vietnamese |
| Tiger | Tiger | Unisex | English |
| Tigger | From Winnie the Pooh | Unisex | English |
| Tiki | Maori figure representing an ancestor. A wooden or stone image of a Polynesian god. | Unisex | English |
| Timber | Wood used as a building material. Also timber-wolf. | Unisex | English |
| Toast | | Unisex | Hebrew |
| Toffee | A hard brown, chewy candy | Unisex | English |
| Truffles | Ball shaped chocolate | Unisex | English |
| Tulip | | Unisex | Hebrew |
| Twinkie | A cream filled cake. | Unisex | English |
| Umberto | Famous giant | Male | German |