| Name | Meaning | Gender | Origin |
|---|
| Silvia | Wooded | Female | Latin |
| Skittles | | Unisex | Hebrew |
| Sky | Sky | Unisex | Norse |
| Slate | | Unisex | Hebrew |
| Smokey | A grayish blue colour. Slang for highway patrol officer | Unisex | English |
| Snickers | A brand of candy bar. | Unisex | English |
| Snow | Snow, fair skinned | Female | English |
| Snowball | | Unisex | Hebrew |
| Snowflake | Single flake or crystal of snow. | Unisex | English |
| Snowy | Covered with snow | Female | English |
| Sooty | Covered with soot | Unisex | English |
| Spade | | Unisex | Hebrew |
| Spirit | Part of the human being associated with the mind. Vigorous or animated state - spirited. Also distilled alcohol. | Unisex | English |
| Spooky | | Unisex | Hebrew |
| Spot | After Data's cat on Star Trek: The Next Generation | Unisex | English |
| Sprinkles | | Unisex | Hebrew |
| Star | Star | Female | Latin |
| Starbuck | Star Deer | Unisex | English |
| Storm | Violent weather | Female | English |
| Suede | Swedish | Unisex | English |
| Sugar | A sweet powder from sugar cane. Slang for sweetheart. | Female | English |
| Sundance | | Unisex | Hebrew |
| Sunila | Dark blue | Female | Indian |
| Sunshine | Light from the sun | Unisex | English |
| Susana | Lily | Female | Hebrew |
| Susanna | Lily | Female | Hebrew |
| Susie | Lily | Female | Hebrew |
| Suvarna | Beautiful color | Female | Sanskrit |
| Suzanne | Lily | Female | Hebrew |
| Suzette | Lily | Female | Hebrew |