| Name | Meaning | Gender | Origin |
|---|
| Silver | Silver (the metal or colour) | Male | English |
| Silvia | Wooded | Female | Latin |
| Skah | White | Male | Native American |
| Skittles | | Unisex | Hebrew |
| Sky | Sky | Unisex | Norse |
| Skye | Cloud | Male | Norse |
| Slate | | Unisex | Hebrew |
| Smith | A smith | Male | English |
| Smokey | A grayish blue colour. Slang for highway patrol officer | Unisex | English |
| Snickers | A brand of candy bar. | Unisex | English |
| Snow | Snow, fair skinned | Female | English |
| Snowball | | Unisex | Hebrew |
| Snowflake | Single flake or crystal of snow. | Unisex | English |
| Snowy | Covered with snow | Female | English |
| Sooty | Covered with soot | Unisex | English |
| Spade | | Unisex | Hebrew |
| Spalding | A field divided | Male | English |
| Spirit | Part of the human being associated with the mind. Vigorous or animated state - spirited. Also distilled alcohol. | Unisex | English |
| Spooky | | Unisex | Hebrew |
| Spot | After Data's cat on Star Trek: The Next Generation | Unisex | English |
| Sprinkles | | Unisex | Hebrew |
| Star | Star | Female | Latin |
| Starbuck | Star Deer | Unisex | English |
| Sterling | Little star - stellar | Male | English |
| Stone | Stone | Male | English |
| Storm | Violent weather | Female | English |
| Suede | Swedish | Unisex | English |
| Sugar | A sweet powder from sugar cane. Slang for sweetheart. | Female | English |
| Sullivan | Keen eye | Male | Gaelic |
| Sundance | | Unisex | Hebrew |