| Name | Meaning | Gender | Origin |
|---|
| Santa | Saintlike | Unisex | Spanish |
| Sarah | Princess | Female | Hebrew |
| Sarge | Noncommissioned Army or Air Force rank | Unisex | English |
| Seamus | Form Of James Supplanter. | Male | English |
| Serafina | From seraphim, meaning fiery ones | Female | Latin |
| Seraphina | From seraphim, meaning fiery ones | Female | Latin |
| Shepherd | One who guards sheeps | Male | English |
| Snoop | To pry into the private affairs of others | Unisex | English |
| Snow | Snow, fair skinned | Female | English |
| Snowball | | Unisex | Hebrew |
| Snowflake | Single flake or crystal of snow. | Unisex | English |
| Snowy | Covered with snow | Female | English |
| Spartacus | From the city of Sparta | Unisex | English |
| Spike | A long, thick sharp-pointed piece of wood or metal | Male | English |
| Spirit | Part of the human being associated with the mind. Vigorous or animated state - spirited. Also distilled alcohol. | Unisex | English |
| Star | Star | Female | Latin |
| Starr | Star | Female | Latin |
| Stella | Star | Female | Latin |
| Suzy | Lily | Female | Hebrew |
| Tasha | (Christ's) birthday | Female | Latin |
| Tashia | (Christ's) birthday | Unisex | Latin |
| Teddy | Gift of God | Male | Greek |
| Tootsie | A girl or young woman. | Unisex | English |
| Turkey | | Unisex | Hebrew |
| Twinkle | | Unisex | Hebrew |
| Tyson | Son of Dye | Male | English |
| Virginia | Maiden | Female | Latin |
| Waite | Guard | Male | English |
| Winston | Joy stone | Male | English |
| Winter | Winter | Female | English |