| Name | Meaning | Gender | Origin |
| Binky | | Unisex | Hebrew |
| Biscuit | A cookie or cracker | Unisex | English |
| Bitsy | | Unisex | Hebrew |
| Blackie | Of the colour black. | Unisex | English |
| Blanca | White | Female | Spanish |
| Bliss | Supreme happiness | Female | English |
| Blizzard | Violent snowstorm | Unisex | English |
| Blondie | Pale yellowish-brown | Unisex | French |
| Blossom | Blossom, flower | Female | English |
| Bo | Handsome | Female | French |
| Bongo | Connected drums played by beating with hands. | Unisex | English |
| Bonnie | Pretty | Female | English |
| Bonsai | The art of growing dwarfed ornamental trees and shrubs. | Unisex | English |
| Boo | | Unisex | Hebrew |
| Boomer | A large full grown kangaroo. A baby boomer. | Unisex | English |
| Boots | | Unisex | Hebrew |
| Brandi | Burning wine | Female | English |
| Brandy | Burning wine | Female | English |
| Brenda | Sword | Female | Norse |
| Brownie | Moist chocolate cake with nuts | Unisex | English |
| Bruiser | A large heavyset man | Unisex | English |
| Bubbles | Thin spherical liquid filled with gas. Irrepressible activity. | Unisex | English |
| Buckwheat | | Unisex | Hebrew |
| Bucky | | Unisex | Hebrew |
| Bug | An insect. A disease-producing microorganism. An error in coding or logic that causes a malfunction in a computer a program. An electronic listening device. An enthusiasm. Slang for annoy. | Unisex | English |
| Bugsy | | Unisex | Hebrew |
| Bunny | Little rabbit | Female | English |
| Buster | One that breaks up something | Unisex | American English |
| Butter | | Unisex | Hebrew |
| Buttercup | A bright yellow flowered plant. Also a term of endearment. | Unisex | English |