| Name | Meaning | Gender | Origin |
|---|
| Rose | Rose | Female | Latin |
| Rosie | Rose | Female | Latin |
| Roxy | Star | Female | Persian |
| Ruby | Red | Female | Latin |
| Rusty | Rusty, full of rust | Unisex | American English |
| Ruth | Friend | Female | Hebrew |
| Sable | Sable (black) | Unisex | English |
| Sadie | Princess | Female | Hebrew |
| Sassy | Lively and spirited | Unisex | English |
| Shade | Sweetly singing | Unisex | African |
| Shadow | Shadow | Unisex | English |
| Sheridan | Long lived treasure | Unisex | Gaelic |
| Sienna | Reddish orange-brown | Female | Italian |
| Sir | | Unisex | Hebrew |
| Smokey | A grayish blue colour. Slang for highway patrol officer | Unisex | English |
| Smudge | A blotch or smear | Unisex | English |
| Snickers | A brand of candy bar. | Unisex | English |
| Sophie | Wisdom | Female | Greek |
| Spot | After Data's cat on Star Trek: The Next Generation | Unisex | English |
| Starbuck | Star Deer | Unisex | English |
| Storm | Violent weather | Female | English |
| Sweet | | Unisex | Hebrew |
| Tex | Of Texas | Unisex | English |
| Tiki | Maori figure representing an ancestor. A wooden or stone image of a Polynesian god. | Unisex | English |
| Timber | Wood used as a building material. Also timber-wolf. | Unisex | English |
| Toby | God is good | Unisex | Hebrew |
| Toffee | A hard brown, chewy candy | Unisex | English |
| Tootsie | A girl or young woman. | Unisex | English |
| Treacle | | Unisex | Hebrew |
| Truffles | Ball shaped chocolate | Unisex | English |