| Name | Meaning | Gender | Origin |
|---|
| Puddles | | Unisex | Hebrew |
| Pumpkin | Large round fruit with orange skin | Unisex | English |
| Rambo | | Unisex | Hebrew |
| Rascal | One that is playfully mischievous | Unisex | English |
| Ren | Water lily | Female | Japanese |
| Rex | King | Male | Latin |
| Riley | Rye clearing | Male | English |
| Rina | Pet form of names in -rina | Female | English |
| Rita | Pearl | Female | Greek |
| Rocio | Covered in dew | Unisex | Spanish |
| Rocky | Battle cry | Male | Germanic |
| Roman | Roman | Unisex | Latin |
| Romy | Sea dew | Unisex | Latin |
| Rosario | Rosary | Female | Spanish |
| Rosie | Rose | Female | Latin |
| Roxy | Star | Female | Persian |
| Rusty | Rusty, full of rust | Unisex | American English |
| Sadie | Princess | Female | Hebrew |
| Sam | He is called god | Male | Hebrew |
| Samantha | Listener | Female | Aramaic |
| Sammy | His name is God | Unisex | Hebrew |
| Sandy | Defending men | Male | Greek |
| Sarge | Noncommissioned Army or Air Force rank | Unisex | English |
| Sasha | Defending men | Unisex | Greek |
| Sasquatch | Has extra toes and hence is a bigfoot | Unisex | English |
| Sassy | Lively and spirited | Unisex | English |
| Saturn | Sixth and second largest planet away from the Sun. | Unisex | English |
| Scar | From The Lion King | Unisex | English |
| Shadow | Shadow | Unisex | English |
| Shark | | Unisex | Hebrew |