| Name | Meaning | Gender | Origin |
|---|
| Pita | The fourth girl baby | Unisex | African |
| Poco | Little. | Unisex | English |
| Psycho | | Unisex | Hebrew |
| Punkin | | Unisex | Hebrew |
| Queen | Female ruler | Unisex | English |
| Radar | | Unisex | Hebrew |
| Rags | | Unisex | Hebrew |
| Rainbow | Rainbow | Unisex | English |
| Rambler | | Unisex | Hebrew |
| Rambo | | Unisex | Hebrew |
| Rebel | One that resists of defies authority | Unisex | English |
| Red | Red | Unisex | English |
| Reggie | Ruler with counsel | Unisex | Germanic |
| Reno | Ruler with counsel | Unisex | Germanic |
| Rocket | To move swiftly and powerfully | Unisex | English |
| Rogue | | Unisex | Hebrew |
| Roman | Roman | Unisex | Latin |
| Roo | | Unisex | Hebrew |
| Rosco | Roe deer wood | Unisex | Norse |
| Rowdy | Boisterous. Western Nickname. | Unisex | English |
| Roxie | Star | Unisex | Persian |
| Rusty | Rusty, full of rust | Unisex | American English |
| Sabre | | Unisex | Hebrew |
| Sammy | His name is God | Unisex | Hebrew |
| Sasha | Defending men | Unisex | Greek |
| Sasquatch | Has extra toes and hence is a bigfoot | Unisex | English |
| Sassy | Lively and spirited | Unisex | English |
| Satan | The Devil and adversary of God | Unisex | English |
| Saturn | Sixth and second largest planet away from the Sun. | Unisex | English |
| Scooter | One who goes suddenly and speedily. | Unisex | English |