| Name | Meaning | Gender | Origin |
|---|
| Perdita | Lost | Female | Latin |
| Pluto | Wealth, riches | Unisex | Greek |
| Pongo | One who smells. | Unisex | English |
| Precious | Loved | Female | English |
| Puddles | | Unisex | Hebrew |
| Puff | Expelling breath, a gust of wind or a small amount of smoke. | Unisex | English |
| Radar | | Unisex | Hebrew |
| Rags | | Unisex | Hebrew |
| Rambler | | Unisex | Hebrew |
| Ren | Water lily | Female | Japanese |
| Rita | Pearl | Female | Greek |
| Rocket | To move swiftly and powerfully | Unisex | English |
| Rocko | | Unisex | Hebrew |
| Roo | | Unisex | Hebrew |
| Rugrat | | Unisex | Hebrew |
| Runt | | Unisex | Hebrew |
| Safari | | Unisex | Hebrew |
| Sausage | Chopped meat stuffed into a prepared casing and cooked. | Unisex | English |
| Scooby | | Unisex | Hebrew |
| Scruff | | Unisex | Hebrew |
| Shadow | Shadow | Unisex | English |
| Shaggy | Bushy and matted (hair), unkempt. | Unisex | English |
| Sky | Sky | Unisex | Norse |
| Slipper | | Unisex | Hebrew |
| Smudge | A blotch or smear | Unisex | English |
| Sniff | A short inhale through the nose. To savour or investigate a smell. | Unisex | English |
| Snoopy | | Unisex | Hebrew |
| Snowy | Covered with snow | Female | English |
| Snuffles | | Unisex | Hebrew |
| Socks | Short stockings finishing above the ankle | Unisex | English |