| Name | Meaning | Gender | Origin |
|---|
| Porsche | Pig | Unisex | Latin |
| Puddles | | Unisex | Hebrew |
| Pumpkin | Large round fruit with orange skin | Unisex | English |
| Quick | Speedy and fast. | Unisex | English |
| Rascal | One that is playfully mischievous | Unisex | English |
| Rhys | Enthusiasm | Unisex | Welsh |
| Romy | Sea dew | Unisex | Latin |
| Roxie | Star | Unisex | Persian |
| Rusty | Rusty, full of rust | Unisex | American English |
| Sammy | His name is God | Unisex | Hebrew |
| Sasha | Defending men | Unisex | Greek |
| Sassy | Lively and spirited | Unisex | English |
| Schnapps | Variety of strong liquor usually associated with Holland | Unisex | English |
| Scooter | One who goes suddenly and speedily. | Unisex | English |
| Scout | Observer | Unisex | American English |
| Shadow | Shadow | Unisex | English |
| Shorty | Of less than average size | Unisex | English |
| Skippy | Master of a Ship | Unisex | American English |
| Slim | Slender in proportion to height. | Unisex | English |
| Socks | Short stockings finishing above the ankle | Unisex | English |
| Sparky | Animated, lively. | Unisex | English |
| Squirt | Slang for a small person | Unisex | English |
| Stumpy | A short, thickset person | Unisex | English |
| Suzie | Lily | Unisex | Hebrew |
| Sweetie | Sweetheart. | Unisex | English |
| Swiper | | Unisex | Hebrew |
| Tinkerbell | | Unisex | Hebrew |
| Tiny | Extremely small | Unisex | English |
| Toby | God is good | Unisex | Hebrew |
| Tootsie | A girl or young woman. | Unisex | English |