| Name | Meaning | Gender | Origin |
|---|
| Shadow | Shadow | Unisex | English |
| Shelby | A place where willows grow | Female | American English |
| Shorty | Of less than average size | Unisex | English |
| Sierra | Mountain range | Female | Spanish |
| Simone | Listening | Female | Hebrew |
| Snickers | A brand of candy bar. | Unisex | English |
| Snowflake | Single flake or crystal of snow. | Unisex | English |
| Snuggles | To curl up closely, cuddle | Unisex | English |
| Sophia | Wisdom | Female | Greek |
| Sophie | Wisdom | Female | Greek |
| Sparky | Animated, lively. | Unisex | English |
| Star | Star | Female | Latin |
| Stella | Star | Female | Latin |
| Stormy | Violent weather | Unisex | English |
| Sugar | A sweet powder from sugar cane. Slang for sweetheart. | Female | English |
| Sunshine | Light from the sun | Unisex | English |
| Sweet | | Unisex | Hebrew |
| Tank | A large metal container. A heavily armed combat vehicle | Unisex | English |
| Tanker | | Unisex | Hebrew |
| Tarzan | White skin | Unisex | Literary |
| Tasha | (Christ's) birthday | Female | Latin |
| T-bone | A thick steak containing a T shaped bone. | Unisex | English |
| Tempest | Storm | Female | English |
| Tex | Of Texas | Unisex | English |
| Thelma | Will | Female | Literary |
| Thunder | Stormy Tempered | Unisex | English |
| Tootsie | A girl or young woman. | Unisex | English |
| Trojan | | Unisex | Hebrew |
| Trouble | A cause of disturbance or difficulty. | Unisex | English |
| Tulip | | Unisex | Hebrew |