| Name | Meaning | Gender | Origin |
| Sonny | Son | Male | English |
| Speckles | | Unisex | Hebrew |
| Spice | Plant used to flavour food or beverages. | Unisex | English |
| Spike | A long, thick sharp-pointed piece of wood or metal | Male | English |
| Spirit | Part of the human being associated with the mind. Vigorous or animated state - spirited. Also distilled alcohol. | Unisex | English |
| Spot | After Data's cat on Star Trek: The Next Generation | Unisex | English |
| Sprinkles | | Unisex | Hebrew |
| Stormy | Violent weather | Unisex | English |
| Streak | | Unisex | Hebrew |
| Stripe | | Unisex | Hebrew |
| Tank | A large metal container. A heavily armed combat vehicle | Unisex | English |
| Taz | Wild Animal, Thrid Born | Unisex | American |
| Theo | Gift of God | Male | Greek |
| Thor | Thunder | Male | Norse |
| Tiger | Tiger | Unisex | English |
| Tigger | From Winnie the Pooh | Unisex | English |
| Timber | Wood used as a building material. Also timber-wolf. | Unisex | English |
| Toby | God is good | Unisex | Hebrew |
| Trix | Blessed Traveller | Unisex | English |
| Tuppence | British for two pence (coins) | Unisex | English |
| Twinkle | | Unisex | Hebrew |
| Twix | Brand of chocolate bar. | Unisex | English |
| Ty | Abbreviation For Names Beginning With Ty-. | Unisex | American English |
| Tyler | Tile maker | Male | English |
| Tyson | Son of Dye | Male | English |
| Vlad | Rule | Male | Russian |
| Whiskey | An alcoholic liquor distilled from grain | Unisex | English |
| Whisper | | Unisex | Hebrew |
| Yogi | Master of oneself | Male | Indian |
| Zen | School of Buddhism that promotes meditation | Unisex | English |