| Name | Meaning | Gender | Origin |
|---|
| Rufus | Red | Male | Latin |
| Rusty | Rusty, full of rust | Unisex | American English |
| Sabre | | Unisex | Hebrew |
| Sabrina | A Welsh river name | Female | Gaelic |
| Sadie | Princess | Female | Hebrew |
| Sam | He is called god | Male | Hebrew |
| Sammy | His name is God | Unisex | Hebrew |
| Samson | Sun | Male | Hebrew |
| Sandy | Defending men | Male | Greek |
| Sasha | Defending men | Unisex | Greek |
| Sassy | Lively and spirited | Unisex | English |
| Satan | The Devil and adversary of God | Unisex | English |
| Satin | Amber | Female | Armenian |
| Scarlet | Scarlet | Female | English |
| Shadow | Shadow | Unisex | English |
| Shark | | Unisex | Hebrew |
| Sheba | Daughter of an oath | Female | Hebrew |
| Sierra | Mountain range | Female | Spanish |
| Sophie | Wisdom | Female | Greek |
| Sparky | Animated, lively. | Unisex | English |
| Spike | A long, thick sharp-pointed piece of wood or metal | Male | English |
| Sugar | A sweet powder from sugar cane. Slang for sweetheart. | Female | English |
| Suki | To like | Female | Japanese |
| Sweetie | Sweetheart. | Unisex | English |
| Tank | A large metal container. A heavily armed combat vehicle | Unisex | English |
| Taryn | King Of Rocky Hill. Variant Of Tarynn. | Female | American English |
| Tasha | (Christ's) birthday | Female | Latin |
| Teddy | Gift of God | Male | Greek |
| Tex | Of Texas | Unisex | English |
| Thunder | Stormy Tempered | Unisex | English |