| Name | Meaning | Gender | Origin |
|---|
| Reba | To tie | Female | Hebrew |
| Rebecca | To tie | Female | Hebrew |
| Rebel | One that resists of defies authority | Unisex | English |
| Reina | Pure | Female | Yiddish |
| Rina | Pet form of names in -rina | Female | English |
| Rosie | Rose | Female | Latin |
| Roxy | Star | Female | Persian |
| Ruby | Red | Female | Latin |
| Rusty | Rusty, full of rust | Unisex | American English |
| Sable | Sable (black) | Unisex | English |
| Sadie | Princess | Female | Hebrew |
| Sakari | Lovely | Female | Indian |
| Samantha | Listener | Female | Aramaic |
| Sammy | His name is God | Unisex | Hebrew |
| Sasha | Defending men | Unisex | Greek |
| Sassy | Lively and spirited | Unisex | English |
| Satin | Amber | Female | Armenian |
| Saturn | Sixth and second largest planet away from the Sun. | Unisex | English |
| Scarlet | Scarlet | Female | English |
| Scout | Observer | Unisex | American English |
| Shadow | Shadow | Unisex | English |
| Shelby | A place where willows grow | Female | American English |
| Simba | Lion | Female | Swahili |
| Sky | Sky | Unisex | Norse |
| Snow | Snow, fair skinned | Female | English |
| Snowball | | Unisex | Hebrew |
| Snowflake | Single flake or crystal of snow. | Unisex | English |
| Snowy | Covered with snow | Female | English |
| Snuggles | To curl up closely, cuddle | Unisex | English |
| Sophie | Wisdom | Female | Greek |