| Name | Meaning | Gender | Origin |
|---|
| Samantha | Listener | Female | Aramaic |
| Sammy | His name is God | Unisex | Hebrew |
| Samson | Sun | Male | Hebrew |
| Sandy | Defending men | Male | Greek |
| Sasha | Defending men | Unisex | Greek |
| Sasquatch | Has extra toes and hence is a bigfoot | Unisex | English |
| Sassy | Lively and spirited | Unisex | English |
| Satan | The Devil and adversary of God | Unisex | English |
| Saturn | Sixth and second largest planet away from the Sun. | Unisex | English |
| Shaka | | Unisex | Hebrew |
| Shark | | Unisex | Hebrew |
| Sheba | Daughter of an oath | Female | Hebrew |
| Sherman | One who shears cloth | Male | English |
| Sierra | Mountain range | Female | Spanish |
| Skip | Master of a Ship | Male | American English |
| Sterling | Little star - stellar | Male | English |
| Sugar | A sweet powder from sugar cane. Slang for sweetheart. | Female | English |
| Taboo | | Unisex | Hebrew |
| Talon | A claw | Male | English |
| Tank | A large metal container. A heavily armed combat vehicle | Unisex | English |
| Tazi | | Unisex | Hebrew |
| Tex | Of Texas | Unisex | English |
| Thunder | Stormy Tempered | Unisex | English |
| Titan | Powerful big man | Unisex | Greek |
| Trojan | | Unisex | Hebrew |
| Tucker | Someone who folds cloth | Male | English |
| Ulysses | Walker | Male | Greek |
| Velvet | Soft | Female | English |
| Vesta | Guardian Of The Sacred Fire | Female | Latin |
| Vicki | Conqueror | Female | Latin |