| Name | Meaning | Gender | Origin |
|---|
| Princess | Royal son | Female | English |
| Psycho | | Unisex | Hebrew |
| Puddles | | Unisex | Hebrew |
| Pummy | | Unisex | Hebrew |
| Pumpkin | Large round fruit with orange skin | Unisex | English |
| Quick | Speedy and fast. | Unisex | English |
| Rage | | Unisex | Hebrew |
| Ranger | Gamekeeper | Male | English |
| Remington | Settlement on the boundary stream | Male | English |
| Rin | Cold | Unisex | Japanese |
| Roach | | Unisex | Hebrew |
| Rowdy | Boisterous. Western Nickname. | Unisex | English |
| Sandler | After the actor Adam Sandler | Male | English |
| Sandy | Defending men | Male | Greek |
| Sarge | Noncommissioned Army or Air Force rank | Unisex | English |
| Sasquatch | Has extra toes and hence is a bigfoot | Unisex | English |
| Sausage | Chopped meat stuffed into a prepared casing and cooked. | Unisex | English |
| Scamp | A mischievous youngster | Unisex | English |
| Schnapps | Variety of strong liquor usually associated with Holland | Unisex | English |
| Scooby | | Unisex | Hebrew |
| Shadow | Shadow | Unisex | English |
| Shiloh | Gift for him | Unisex | Hebrew |
| Shorty | Of less than average size | Unisex | English |
| Shredder | | Unisex | Hebrew |
| Skeeter | | Unisex | Hebrew |
| Skittles | | Unisex | Hebrew |
| Skunk | | Unisex | Hebrew |
| Sleepy | | Unisex | Hebrew |
| Slim | Slender in proportion to height. | Unisex | English |
| Smokey | A grayish blue colour. Slang for highway patrol officer | Unisex | English |